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- Title
Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype.
- Authors
Ricardo, Sara; Vieira, André Filipe; Gerhard, Renê; Leitão, Dina; Pinto, Regina; Cameselle-Teijeiro, Jorge F; Milanezi, Fernanda; Schmitt, Fernando; Paredes, Joana
- Abstract
The study of CD44/CD24 and ALDH1 expression is the most accurate method to identify cancer stem cells (CSC) from breast cancer populations. However, the overlap between CD44(+)CD24(-/low) and ALDH1(high) CSC phenotypes in breast cancer seems to be very small, as well as their distribution among intrinsic breast cancer subtypes. Due to this discrepancy, it is imperative to improve the understanding of breast CSC marker distribution.
- Publication
Journal of clinical pathology, 2011, Vol 64, Issue 11, p937
- ISSN
1472-4146
- Publication type
Journal Article
- DOI
10.1136/jcp.2011.090456