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- Title
EpCAM expression in primary tumour tissues and metastases: an immunohistochemical analysis.
- Authors
Spizzo, Gilbert; Fong, Dominic; Wurm, Martin; Ensinger, Christian; Obrist, Peter; Hofer, Carina; Mazzoleni, Guido; Gastl, Guenther; Went, Philip
- Abstract
Epithelial cell adhesion molecule (EpCAM) is a cell surface protein with oncogenic features that is expressed on healthy human epithelia and corresponding malignant tumours. EpCAM expression frequently correlates with more aggressive tumour behaviour and new EpCAM-specific therapeutic agents have recently been approved for clinical use in patients with cancer. However, no consensus exists on how and when to evaluate EpCAM expression in patients with cancer.
- Publication
Journal of clinical pathology, 2011, Vol 64, Issue 5, p415
- ISSN
1472-4146
- Publication type
Journal Article
- DOI
10.1136/jcp.2011.090274