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Title
MUC4 is increased in high grade intraepithelial neoplasia in Barrett's oesophagus and is associated with a proapoptotic Bax to Bcl-2 ratio.
Authors
Bax, D A; Haringsma, J; Einerhand, A W C; van Dekken, H; Blok, P; Siersema, P D; Kuipers, E J; Kusters, J G
Abstract
Patients with Barrett's oesophagus (BO) are at risk of oesophageal adenocarcinoma. Because the pattern of mucosal mucins changes during neoplastic progression, it may serve as a marker of intraepithelial neoplasia.
Publication
Journal of clinical pathology, 2004, Vol 57, Issue 12, p1267