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- Title
CD133 positive endothelial progenitor cells contribute to the tumour vasculature in non-small cell lung cancer.
- Authors
Hilbe, W; Dirnhofer, S; Oberwasserlechner, F; Schmid, T; Gunsilius, E; Hilbe, G; Wöll, E; Kähler, C M
- Abstract
Recent results generated in a mouse model suggest that tumour angiogenesis/vasculogenesis can be initiated and maintained by bone marrow derived endothelial progenitor cells. This present study investigated the distribution and frequency of CD133 positive endothelial progenitor cells in patients with non-small cell lung cancer (NSCLC) (tumour tissue and tumour free lung regions) and healthy controls using fresh frozen specimens. The novel marker CD133 identifies human haemopoetic precursor cells, in addition to human endothelial progenitor cells.
- Publication
Journal of clinical pathology, 2004, Vol 57, Issue 9, p965
- ISSN
0021-9746
- Publication type
Journal Article
- DOI
10.1136/jcp.2004.016444