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- Title
Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families.
- Authors
Friedl, W; Caspari, R; Sengteller, M; Uhlhaas, S; Lamberti, C; Jungck, M; Kadmon, M; Wolf, M; Fahnenstich, J; Gebert, J; Möslein, G; Mangold, E; Propping, P
- Abstract
In familial adenomatous polyposis (FAP), correlations between site of mutation in the adenomatous polyposis coli (APC) gene and severity of colonic polyposis or extracolonic manifestations are well known. While mutation analysis is important for predictive diagnosis in persons at risk, its relevance for clinical management of individual patients is open to question.
- Publication
Gut, 2001, Vol 48, Issue 4, p515
- ISSN
0017-5749
- Publication type
Journal Article
- DOI
10.1136/gut.48.4.515