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- Title
Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis.
- Authors
Ohba, K; Omagari, K; Nakamura, T; Ikuno, N; Saeki, S; Matsuo, I; Kinoshita, H; Masuda, J; Hazama, H; Sakamoto, I; Kohno, S
- Abstract
Spontaneous regression of hepatocellular carcinoma is a rare phenomenon. Abscopal regression of tumours resulting from the effect of irradiation of a tissue on a remote non-irradiated tissue is also rare. The case of a 76 year old Japanese man with hepatocellular carcinoma that regressed after radiotherapy for thoracic vertebral bone metastasis is described. Serum levels of tumour necrosis factor-alpha increased after radiotherapy. The findings suggests that such abscopal related regression may be associated with host immune response, involving cytokines such as tumour necrosis factor-alpha.
- Publication
Gut, 1998, Vol 43, Issue 4, p575
- ISSN
0017-5749
- Publication type
Journal Article
- DOI
10.1136/gut.43.4.575