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- Title
Marked increase in gastric acid secretory capacity after omeprazole treatment.
- Authors
Waldum, H L; Arnestad, J S; Brenna, E; Eide, I; Syversen, U; Sandvik, A K
- Abstract
In contrast with the histamine2 (H2) blockers, proton pump inhibitors have not been shown to give rebound hypersecretion of acid. Taking into consideration the hyperplasia of the enterochromaffin-like (ECL) cell provoked by hypergastrinaemia secondary to profound acid inhibition and the central role of histamine from ECL cells in the regulation of acid secretion, the lack of any rebound acid hypersecretion after treatment with proton pump inhibitors has been questioned.
- Publication
Gut, 1996, Vol 39, Issue 5, p649
- ISSN
0017-5749
- Publication type
Journal Article
- DOI
10.1136/gut.39.5.649