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- Title
Transforming growth factor beta 1: in situ expression in the liver of patients with chronic hepatitis C treated with alpha interferon.
- Authors
Bedossa, P; Poynard, T; Mathurin, P; Lemaigre, G; Chaput, J C
- Abstract
In a semiquantitative assessment of the expression of transforming growth factor (TGF) beta 1 in liver biopsy specimens from patients with chronic hepatitis C, treatment with interferon alfa-2b (3 million units (MU) three times weekly) decreased the expression of TGF beta 1 in six of seven patients. The reduction in TGF beta 1 correlated significantly with the scores for inflammation (p < 0.05) and necrosis (p < 0.05), but not with the alanine aminotransferase activities (p = 0.36) or the score for fibrosis (p = 0.86).
- Publication
Gut, 1993, Vol 34, Issue 2 Suppl, pS146
- ISSN
0017-5749
- Publication type
Journal Article
- DOI
10.1136/gut.34.2_suppl.s146