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- Title
Increased intestinal permeability in ankylosing spondylitis--primary lesion or drug effect?
- Authors
Morris, A J; Howden, C W; Robertson, C; Duncan, A; Torley, H; Sturrock, R D; Russell, R I
- Abstract
We have found increased small intestinal permeability to 51Cr-ethylenediaminetetra acetate in patients with ankylosing spondylitis compared with controls. There is no significant difference between patients with ankylosing spondylitis and patients with rheumatoid arthritis taking non-steroidal anti-inflammatory drugs (NSAID). The increased intestinal permeability in ankylosing spondylitis is independent of disease activity. These findings suggest that the increased permeability is caused by NSAID treatment and is probably not a primary lesion of small bowel mucosa.
- Publication
Gut, 1991, Vol 32, Issue 12, p1470
- ISSN
0017-5749
- Publication type
Journal Article
- DOI
10.1136/gut.32.12.1470