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- Title
CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
- Authors
Ogino, Shuji; Nosho, Katsuhiko; Kirkner, Gregory J; Kawasaki, Takako; Meyerhardt, Jeffrey A; Loda, Massimo; Giovannucci, Edward L; Fuchs, Charles S
- Abstract
The CpG island methylator phenotype (CIMP), characterised by widespread promoter methylation, is associated with microsatellite instability (MSI) and BRAF mutation in colorectal cancer. The independent effect of CIMP, MSI and BRAF mutation on prognosis remains uncertain.
- Publication
Gut, 2009, Vol 58, Issue 1, p90
- ISSN
1468-3288
- Publication type
Journal Article
- DOI
10.1136/gut.2008.155473