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- Title
High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas.
- Authors
Le Gouvello, S; Bastuji-Garin, S; Aloulou, N; Mansour, H; Chaumette, M-T; Berrehar, F; Seikour, A; Charachon, A; Karoui, M; Leroy, K; Farcet, J-P; Sobhani, I
- Abstract
Colorectal cancer (CRC) harbours different types of DNA alterations, including microsatellite instability (MSI). Cancers with high levels of MSI (MSI-H) are considered to have a good prognosis, probably related to lymphocyte infiltration within tumours. The aim of the present study was to characterise the intratumoural expression of markers associated with the antitumour immune response in mismatch repair (MMR)-proficient (MSS) colon cancers.
- Publication
Gut, 2008, Vol 57, Issue 6, p772
- ISSN
1468-3288
- Publication type
Journal Article
- DOI
10.1136/gut.2007.123794