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- Title
Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo.
- Authors
Brockschmidt, C; Hirner, H; Huber, N; Eismann, T; Hillenbrand, A; Giamas, G; Radunsky, B; Ammerpohl, O; Bohm, B; Henne-Bruns, D; Kalthoff, H; Leithäuser, F; Trauzold, A; Knippschild, U
- Abstract
Pancreatic ductal adenocarcinomas (PDACs) are highly resistant to treatment due to changes in various signalling pathways. CK1 isoforms play important regulatory roles in these pathways.
- Publication
Gut, 2008, Vol 57, Issue 6, p799
- ISSN
1468-3288
- Publication type
Journal Article
- DOI
10.1136/gut.2007.123695