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- Title
Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential.
- Authors
di Bonzo, L Valfrè; Ferrero, I; Cravanzola, C; Mareschi, K; Rustichell, D; Novo, E; Sanavio, F; Cannito, S; Zamara, E; Bertero, M; Davit, A; Francica, S; Novelli, F; Colombatto, S; Fagioli, F; Parola, M
- Abstract
Mesenchymal stem cells from bone marrow (MSCs) may have the potential to differentiate in vitro and in vivo into hepatocytes. We investigated whether transplanted human MSCs (hMSCs) may engraft the liver of non-obese diabetic severe combined immuno-deficient (NOD/SCID) mice and differentiate into cells of hepatic lineage.
- Publication
Gut, 2008, Vol 57, Issue 2, p223
- ISSN
1468-3288
- Publication type
Journal Article
- DOI
10.1136/gut.2006.111617