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- Title
Bacterial and fungal microbiota in relation to probiotic therapy (VSL#3) in pouchitis.
- Authors
Kühbacher, T; Ott, S J; Helwig, U; Mimura, T; Rizzello, F; Kleessen, B; Gionchetti, P; Blaut, M; Campieri, M; Fölsch, U R; Kamm, M A; Schreiber, S
- Abstract
The intestinal microbiota plays a critical role in the pathophysiology of pouchitis, a major complication after ileal pouch anal anastomosis in patients with ulcerative colitis. Recently, controlled trials have demonstrated that probiotics are effective in maintenance of remission in pouchitis patients. However, the mechanism by which therapy with probiotics works remains elusive. This study explores the role of the bacterial and fungal flora in a controlled trial for maintenance of remission in pouchitis patients with the probiotic VSL#3 compound.
- Publication
Gut, 2006, Vol 55, Issue 6, p833
- ISSN
0017-5749
- Publication type
Journal Article
- DOI
10.1136/gut.2005.078303