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- Title
Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1.
- Authors
Walsh, M J; Jonsson, J R; Richardson, M M; Lipka, G M; Purdie, D M; Clouston, A D; Powell, E E
- Abstract
Interferon alpha (IFN-alpha) activated cellular signalling is negatively regulated by inhibitory factors, including the suppressor of cytokine signalling (SOCS) family. The effects of host factors such as obesity on hepatic expression of these inhibitory factors in subjects with chronic hepatitis C virus (HCV) are unknown.
- Publication
Gut, 2006, Vol 55, Issue 4, p529
- ISSN
0017-5749
- Publication type
Journal Article
- DOI
10.1136/gut.2005.069674