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- Title
BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.
- Authors
Kambara, T; Simms, L A; Whitehall, V L J; Spring, K J; Wynter, C V A; Walsh, M D; Barker, M A; Arnold, S; McGivern, A; Matsubara, N; Tanaka, N; Higuchi, T; Young, J; Jass, J R; Leggett, B A
- Abstract
Mutations in BRAF have been linked with colorectal cancers (CRC) showing high level microsatellite instability (MSI-H). However, the distribution of BRAF mutations in MSI-H cancers remains to be clarified with respect to precursor lesions and the CpG island methylator phenotype (CIMP).
- Publication
Gut, 2004, Vol 53, Issue 8, p1137
- ISSN
0017-5749
- Publication type
Journal Article
- DOI
10.1136/gut.2003.037671