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- Title
Multicentre, short-term therapeutic trial of disodium cromoglycate, with and without prednisone, in adults with asthma.
- Authors
Gebbie, T; Harris, E A; O'Donnell, T V; Spears, G F
- Abstract
A total of 117 asthmatic patients were studied in a double-blind, cross-over trial with half-periods of three weeks in which disodium cromoglycate (D.S.C.G.) was compared with an inactive preparation. D.S.C.G. improved spirometric measurements, at a very high level of statistical significance, more than did placebo. The mean advantage of D.S.C.G. was less than 10% after three weeks. Symptomatic improvement by D.S.C.G. was small though significant; it was not correlated with spirometric improvement. A history of chronic cough was the only clinical characteristic associated with a better-than-average spirometric response to D.S.C.G.
- Publication
British medical journal, 1972, Vol 4, Issue 5840, p576
- ISSN
0007-1447
- Publication type
Journal Article
- DOI
10.1136/bmj.4.5840.576