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- Title
Duration of treatment for urinary tract infections in children.
- Authors
Stansfeld, J M
- Abstract
In a double-blind trial 45 children aged 6 months to 14 years with Escherichia coli infections of the urinary tract were given co-trimoxazole for two weeks and then allotted at random to one of two treatment groups for the remainder of six months; one continued with the active drug and the other with dummy tablets of identical appearance. Of the 24 children who took co-trimoxazole for two weeks and the 21 who took it for six months, 11 and 10, respectively, remained without further infections for at least a year. Over 90% of the reinfections occurred within five months of stopping the antibiotics, and the longer treatment did not cause any delay in their appearance. Thus probably a six-month course of treatment is no more likely to achieve a cure than a two-week course; nevertheless, no infection occurred during treatment, and there may be an advantage in continuing with antibiotics in small dosage.
- Publication
British medical journal, 1975, Vol 3, Issue 5975, p65
- ISSN
0007-1447
- Publication type
Journal Article
- DOI
10.1136/bmj.3.5975.65