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- Title
Nitric oxide synthase-derived plasma nitrite predicts exercise capacity.
- Authors
Rassaf, Tienush; Lauer, Thomas; Heiss, Christian; Balzer, Jan; Mangold, Sarah; Leyendecker, Thorsten; Rottler, Jessica; Drexhage, Christine; Meyer, Christian; Kelm, Malte
- Abstract
Nitrite is the main oxidation product of nitric oxide (NO) in plasma. It sensitively reflects changes in endothelial NO synthase (eNOS) activity under fasting conditions and serves as an endocrine NO donor, contributing to the regulation of blood flow through reaction with haemoglobin. As NO is necessary to maintain an adequate vascular response to the increased demands of blood flow, it is believed to be important for vasodilation induced by exercise.
- Publication
British journal of sports medicine, 2007, Vol 41, Issue 10, p669
- ISSN
1473-0480
- Publication type
Journal Article
- DOI
10.1136/bjsm.2007.035758