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- Title
Nucleation of monosodium urate crystals.
- Authors
Wilcox, W R; Khalaf, A A
- Abstract
(1) Calcium greatly increased crystallization of monosodium urate in otherwise pure water, by enhancing both nucleation and growth. (2) Acid accelerated urate nucleation, both by its direct action and indirectly by increasing the free calcium in physiological fluids. (3) Synovial fluid from one gouty patient accelerated urate nucleation, while that from one rheumatoid patient inhibited nucleation. (4) X-rays, collagen, ethyl alcohol, cupric ion, and potassium ion all had negligible influence on urate nucleation. (5) Mechanical shock greatly increased urate nucleation.
- Publication
Annals of the rheumatic diseases, 1975, Vol 34, Issue 4, p332
- ISSN
0003-4967
- Publication type
Journal Article
- DOI
10.1136/ard.34.4.332