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- Title
Polymorphisms of the IgH enhancer HS1.2 and risk of systemic lupus erythematosus.
- Authors
Frezza, Domenico; Tolusso, Barbara; Giambra, Vincenzo; Gremese, Elisa; Marchini, Maurizio; Nowik, Marcin; Serone, Eliseo; D'Addabbo, Pietro; Mattioli, Claudia; Canestri, Silvia; Petricca, Luca; D'Antona, Graziella; Birshtein, Barbara K; Scorza, Raffaella; Ferraccioli, Gianfranco
- Abstract
To determine whether the allelic frequency variation of the HS1.2 enhancer of the immunoglobulin heavy chain (IgH) 3' regulatory region (3'RR-1) locus represents a risk factor for systemic lupus erythematosus (SLE) and to identify a possible functional difference in the two most frequent alleles (*1 and *2) in binding nuclear factor- κB (NF-κB) and Sp1.
- Publication
Annals of the rheumatic diseases, 2012, Vol 71, Issue 8, p1309
- ISSN
1468-2060
- Publication type
Journal Article
- DOI
10.1136/ard.2010.147025