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- Title
Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study.
- Authors
Orozco, Gisela; Eyre, Steve; Hinks, Anne; Ke, Xiayi; Wilson, Anthony G; Bax, Deborah E; Morgan, Ann W; Emery, Paul; Steer, Sophia; Hocking, Lynne; Reid, David M; Wordsworth, Paul; Harrison, Pille; Thomson, Wendy; Barton, Anne; Worthington, Jane; Wellcome Trust Case Control consortium YEAR Consortium
- Abstract
A recent meta-analysis of published genome-wide association studies (GWAS) in populations of European descent reported novel associations of markers mapping to the CD40, CCL21 and CDK6 genes with rheumatoid arthritis (RA) susceptibility while a large-scale, case-control association study in a Japanese population identified association with multiple single nucleotide polymorphisms (SNPs) in the CD244 gene. The aim of the current study was to validate these potential RA susceptibility markers in a UK population.
- Publication
Annals of the rheumatic diseases, 2010, Vol 69, Issue 5, p813
- ISSN
1468-2060
- Publication type
Journal Article
- DOI
10.1136/ard.2009.109579