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- Title
Serum IgG antibodies to peptidylarginine deiminase 4 predict radiographic progression in patients with rheumatoid arthritis treated with tumour necrosis factor-alpha blocking agents.
- Authors
Halvorsen, E H; Haavardsholm, E A; Pollmann, S; Boonen, A; van der Heijde, D; Kvien, T K; Molberg, Ø
- Abstract
Peptidylarginine deiminase 4 (PAD4) may generate epitopes targeted by anticitrullinated protein antibodies in rheumatoid arthritis (RA). A subset of patients with RA has serum autoantibodies to human recombinant PAD4 (hPAD4). Here, we assessed whether anti-hPAD4 status in RA predicted disease outcome after antitumour necrosis factor (anti-TNF)-alpha therapy.
- Publication
Annals of the rheumatic diseases, 2009, Vol 68, Issue 2, p249
- ISSN
1468-2060
- Publication type
Journal Article
- DOI
10.1136/ard.2008.094490