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- Title
Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1).
- Authors
Sugiyama, N; Nakashima, H; Yoshimura, T; Sadanaga, A; Shimizu, S; Masutani, K; Igawa, T; Akahoshi, M; Miyake, K; Takeda, A; Yoshimura, A; Hamano, S; Yoshida, H
- Abstract
In the present work, we investigate the role of interleukin (IL)27/IL27 receptor alpha (Ralpha) (WSX-1) in the development of autoimmune disorders in the MRL/lpr mouse, which is considered as an experimental model of systemic lupus erythaematosus (SLE) in humans.
- Publication
Annals of the rheumatic diseases, 2008, Vol 67, Issue 10, p1461
- ISSN
1468-2060
- Publication type
Journal Article
- DOI
10.1136/ard.2007.077537