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- Title
Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls.
- Authors
Jacobi, A M; Goldenberg, D M; Hiepe, F; Radbruch, A; Burmester, G R; Dörner, T
- Abstract
B lymphocytes have been implicated in the pathogenesis of lupus and other autoimmune diseases, resulting in the introduction of B cell-directed therapies. Epratuzumab, a humanised anti-CD22 monoclonal antibody, is currently in clinical trials, although its effects on patients' B cells are not completely understood.
- Publication
Annals of the rheumatic diseases, 2008, Vol 67, Issue 4, p450
- ISSN
1468-2060
- Publication type
Journal Article
- DOI
10.1136/ard.2007.075762