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- Title
Vitamin D and autoimmunity: new aetiological and therapeutic considerations.
- Authors
Arnson, Yoav; Amital, Howard; Shoenfeld, Yehuda
- Abstract
Vitamin D is frequently prescribed by rheumatologists to prevent and treat osteoporosis. Several observations have shown that vitamin D inhibits proinflammatory processes by suppressing the enhanced activity of immune cells that take part in the autoimmune reaction. Moreover, recent evidence strongly suggests that vitamin D supplementation may be therapeutically beneficial, particularly for Th1-mediated autoimmune disorders. Some reports imply that vitamin D may even be preventive in certain disorders such as multiple sclerosis and diabetes type 1. It seems that vitamin D has crossed the boundaries of calcium metabolism and has become a significant factor in a number of physiological functions, specifically as a biological inhibitor of inflammatory hyperactivity.
- Publication
Annals of the rheumatic diseases, 2007, Vol 66, Issue 9, p1137
- ISSN
0003-4967
- Publication type
Journal Article
- DOI
10.1136/ard.2007.069831