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- Title
Safety and efficacy of leflunomide in primary Sjögren's syndrome: a phase II pilot study.
- Authors
van Woerkom, J M; Kruize, A A; Geenen, R; van Roon, E N; Goldschmeding, R; Verstappen, S M M; van Roon, J A G; Bijlsma, J W J
- Abstract
For invalidating symptoms in primary Sjögren's syndrome (pSS), there is still a need for easy-to-administer, cost-effective and well-tolerated systemic treatment. Leflunomide (LEF) is structurally unrelated to other immunomodulatory drugs and might be efficacious in pSS, given its characteristic immunoregulatory modes of action.
- Publication
Annals of the rheumatic diseases, 2007, Vol 66, Issue 8, p1026
- ISSN
0003-4967
- Publication type
Journal Article
- DOI
10.1136/ard.2006.060905