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- Title
Role of nitric oxide in the regulation of T cell functions.
- Authors
Niedbala, W; Cai, B; Liew, F Y
- Abstract
There is a close relation between T helper (Th) 1 cells and nitric oxide in disease. Thus it is possible that a reciprocal regulatory mechanism exists between them. This paper briefly describes the experimental studies which have helped elucidate the mechanism by which nitric oxide selectively enhances Th 1 cell proliferation and the potential effect of nitric oxide on regulatory T (Treg) cells. On the basis of the results the authors propose that nitric oxide represents an additional signal for the induction of T cell subset response, contributing to the increasingly complex network of immune regulation essential for health and disease.
- Publication
Annals of the rheumatic diseases, 2006, Vol 65 Suppl 3, piii37
- ISSN
0003-4967
- Publication type
Journal Article
- DOI
10.1136/ard.2006.058446