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- Title
DNA methylome signature in rheumatoid arthritis.
- Authors
Nakano, Kazuhisa; Whitaker, John W; Boyle, David L; Wang, Wei; Firestein, Gary S
- Abstract
Epigenetics can influence disease susceptibility and severity. While DNA methylation of individual genes has been explored in autoimmunity, no unbiased systematic analyses have been reported. Therefore, a genome-wide evaluation of DNA methylation loci in fibroblast-like synoviocytes (FLS) isolated from the site of disease in rheumatoid arthritis (RA) was performed.
- Publication
Annals of the rheumatic diseases, 2013, Vol 72, Issue 1, p110
- ISSN
1468-2060
- Publication type
Journal Article
- DOI
10.1136/annrheumdis-2012-201526