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- Title
Translating Mendelian and complex inheritance of Alzheimer's disease genes for predicting unique personal genome variants.
- Authors
Regan, Kelly; Wang, Kanix; Doughty, Emily; Li, Haiquan; Li, Jianrong; Lee, Younghee; Kann, Maricel G; Lussier, Yves A
- Abstract
Although trait-associated genes identified as complex versus single-gene inheritance differ substantially in odds ratio, the authors nonetheless posit that their mechanistic concordance can reveal fundamental properties of the genetic architecture, allowing the automated interpretation of unique polymorphisms within a personal genome.
- Publication
Journal of the American Medical Informatics Association : JAMIA, 2012, Vol 19, Issue 2, p306
- ISSN
1527-974X
- Publication type
Journal Article
- DOI
10.1136/amiajnl-2011-000656