We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Facilitating adverse drug event detection in pharmacovigilance databases using molecular structure similarity: application to rhabdomyolysis.
- Authors
Vilar, Santiago; Harpaz, Rave; Chase, Herbert S; Costanzi, Stefano; Rabadan, Raul; Friedman, Carol
- Abstract
Adverse drug events (ADE) cause considerable harm to patients, and consequently their detection is critical for patient safety. The US Food and Drug Administration maintains an adverse event reporting system (AERS) to facilitate the detection of ADE in drugs. Various data mining approaches have been developed that use AERS to detect signals identifying associations between drugs and ADE. The signals must then be monitored further by domain experts, which is a time-consuming task.
- Publication
Journal of the American Medical Informatics Association : JAMIA, 2011, Vol 18 Suppl 1, pi73
- ISSN
1527-974X
- Publication type
Journal Article
- DOI
10.1136/amiajnl-2011-000417