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- Title
Clinical course of patients with major histocompatibility complex class II deficiency.
- Authors
Saleem, M A; Arkwright, P D; Davies, E G; Cant, A J; Veys, P A
- Abstract
The clinical course of 10 children who have been diagnosed with major histocompatibility complex (MHC) class II deficiency (bare lymphocyte syndrome) in the UK over the past eight years is described. They have had a generally poor prognosis, with only two of the 10 still alive despite eight attempts at bone marrow transplantation in six patients. Overwhelming viral infection was the predominant cause of death. Alternative transplant strategies or novel therapies are required for these patients.
- Publication
Archives of disease in childhood, 2000, Vol 83, Issue 4, p356
- ISSN
1468-2044
- Publication type
Journal Article
- DOI
10.1136/adc.83.4.356