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- Title
Prevalence of atopy and exercise-induced bronchial lability in relatives of patients with cystic fibrosis.
- Authors
Counahan, R; Mearns, M B
- Abstract
Skin tests and exercise tests were performed on children with cystic fibrosis (CF) and first-degree relatives of CF children. Positive skin tests were found in 56% of patients and 19% of relatives, but the prevalence of atopy in CF patients bore no relationship to its prevalence in their relatives. Increased 0ronchial lability, mainly due to bronchoconstriction, was present in 54% of patients and 27% of relatives. The results showed that increased prevalence of bronchial lability, but not atopy, is found in first-degree relatives of CF children, and that the abnormal lability and atopy found in CF children does not indicate a familial allergic background.
- Publication
Archives of disease in childhood, 1975, Vol 50, Issue 6, p477
- ISSN
1468-2044
- Publication type
Journal Article
- DOI
10.1136/adc.50.6.477