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- Title
Oxidative stress in yeast.
- Authors
Lushchak, V I
- Abstract
The mechanisms of production and elimination of reactive oxygen species in the cells of the budding yeast Saccharomyces cerevisiae are analyzed. Coordinative role of special regulatory proteins including Yap1p, Msn2/4p, and Skn7p (Pos9p) in regulation of defense mechanisms in S. cerevisiae is described. A special section is devoted to two other well-studied species from the point of view of oxidative stress -- Schizosaccharomyces pombe and Candida albicans. Some examples demonstrating the use of yeast for investigation of apoptosis, aging, and some human diseases are given in the conclusion part.
- Publication
Biochemistry. Biokhimiia, 2010, Vol 75, Issue 3, p281
- ISSN
1608-3040
- Publication type
Journal Article
- DOI
10.1134/s0006297910030041