Title

Supramolecular Systems Based on Sodium Alginate and Viologen Calix[4]resorcinol Capable of Encapsulating Hydrophobic Compounds.

Authors

Kashapov, R. R.; Razuvayeva, Yu. S.; Ziganshina, A. Yu.; Sapunova, A. S.; Voloshina, A. D.; Salnikov, V. V.; Zakharova, L. Ya.

Abstract

The supramolecular system based on viologen calix[4]resorcinol and sodium alginate in an aqueous medium was studied by a set of physicochemical methods. It was found that sodium alginate and viologen calix[4]resorcinol in the range of macrocycle : polymer concentration ratios from 1 : 2 to 1 : 10 form stable nanoparticles capable of encapsulating biologically active hydrophobic substances. In the presence of encapsulated substrates, the selectivity of the action of quercetin and oleic acid against M-HeLa tumor cells increases by 2.47 and 1.14 times, respectively.

Publication

Russian Journal of General Chemistry, 2023, Vol 93, Issue 5, p1144

ISSN

1070-3632

Publication type

Academic Journal

DOI

10.1134/S1070363223050158