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- Title
fw2.2: a quantitative trait locus key to the evolution of tomato fruit size.
- Authors
Frary, A; Nesbitt, T C; Grandillo, S; Knaap, E; Cong, B; Liu, J; Meller, J; Elber, R; Alpert, K B; Tanksley, S D
- Abstract
Domestication of many plants has correlated with dramatic increases in fruit size. In tomato, one quantitative trait locus (QTL), fw2.2, was responsible for a large step in this process. When transformed into large-fruited cultivars, a cosmid derived from the fw2.2 region of a small-fruited wild species reduced fruit size by the predicted amount and had the gene action expected for fw2.2. The cause of the QTL effect is a single gene, ORFX, that is expressed early in floral development, controls carpel cell number, and has a sequence suggesting structural similarity to the human oncogene c-H-ras p21. Alterations in fruit size, imparted by fw2.2 alleles, are most likely due to changes in regulation rather than in the sequence and structure of the encoded protein.
- Publication
Science (New York, N.Y.), 2000, Vol 289, Issue 5476, p85
- ISSN
0036-8075
- Publication type
Journal Article
- DOI
10.1126/science.289.5476.85