We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Pharmacogenomics: translating functional genomics into rational therapeutics.
- Authors
Evans, W E; Relling, M V
- Abstract
Genetic polymorphisms in drug-metabolizing enzymes, transporters, receptors, and other drug targets have been linked to interindividual differences in the efficacy and toxicity of many medications. Pharmacogenomic studies are rapidly elucidating the inherited nature of these differences in drug disposition and effects, thereby enhancing drug discovery and providing a stronger scientific basis for optimizing drug therapy on the basis of each patient's genetic constitution.
- Publication
Science (New York, N.Y.), 1999, Vol 286, Issue 5439, p487
- ISSN
0036-8075
- Publication type
Journal Article
- DOI
10.1126/science.286.5439.487