We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Mitochondria and apoptosis.
- Authors
Green, D R; Reed, J C
- Abstract
A variety of key events in apoptosis focus on mitochondria, including the release of caspase activators (such as cytochrome c), changes in electron transport, loss of mitochondrial transmembrane potential, altered cellular oxidation-reduction, and participation of pro- and antiapoptotic Bcl-2 family proteins. The different signals that converge on mitochondria to trigger or inhibit these events and their downstream effects delineate several major pathways in physiological cell death.
- Publication
Science (New York, N.Y.), 1998, Vol 281, Issue 5381, p1309
- ISSN
0036-8075
- Publication type
Journal Article
- DOI
10.1126/science.281.5381.1309