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- Title
Natural variation in a Drosophila clock gene and temperature compensation.
- Authors
Sawyer, L A; Hennessy, J M; Peixoto, A A; Rosato, E; Parkinson, H; Costa, R; Kyriacou, C P
- Abstract
The threonine-glycine (Thr-Gly) encoding repeat within the clock gene period of Drosophila melanogaster is polymorphic in length. The two major variants (Thr-Gly)17 and (Thr-Gly)20 are distributed as a highly significant latitudinal cline in Europe and North Africa. Thr-Gly length variation from both wild-caught and transgenic individuals is related to the flies' ability to maintain a circadian period at different temperatures. This phenomenon provides a selective explanation for the geographical distribution of Thr-Gly lengths and gives a rare glimpse of the interplay between molecular polymorphism, behavior, population biology, and natural selection.
- Publication
Science (New York, N.Y.), 1997, Vol 278, Issue 5346, p2117
- ISSN
0036-8075
- Publication type
Journal Article
- DOI
10.1126/science.278.5346.2117