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- Title
Genome sequence of a polydnavirus: insights into symbiotic virus evolution.
- Authors
Espagne, Eric; Dupuy, Catherine; Huguet, Elisabeth; Cattolico, Laurence; Provost, Bertille; Martins, Nathalie; Poirié, Marylène; Periquet, Georges; Drezen, Jean Michel
- Abstract
Little is known of the fate of viruses involved in long-term obligatory associations with eukaryotes. For example, many species of parasitoid wasps have symbiotic viruses to manipulate host defenses and to allow development of parasitoid larvae. The complete nucleotide sequence of the DNA enclosed in the virus particles injected by a parasitoid wasp revealed a complex organization, resembling a eukaryote genomic region more than a viral genome. Although endocellular symbiont genomes have undergone a dramatic loss of genes, the evolution of symbiotic viruses appears to be characterized by extensive duplication of virulence genes coding for truncated versions of cellular proteins.
- Publication
Science (New York, N.Y.), 2004, Vol 306, Issue 5694, p286
- ISSN
1095-9203
- Publication type
Journal Article
- DOI
10.1126/science.1103066