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- Title
The needle length of bacterial injectisomes is determined by a molecular ruler.
- Authors
Journet, Laure; Agrain, Céline; Broz, Petr; Cornelis, Guy R
- Abstract
Size determination represents a fundamental requirement for multicomponent biological structures. Some pathogenic bacteria possess a weapon derived from the flagellum. Like the flagellum, this type-III secretion apparatus, called the injectisome, has a transmembrane basal body, but the external component is a needle-like structure instead of a hook and a filament. Here, we provide evidence that the length of this needle is determined by the size of a protein, YscP, acting as a molecular ruler.
- Publication
Science (New York, N.Y.), 2003, Vol 302, Issue 5651, p1757
- ISSN
1095-9203
- Publication type
Journal Article
- DOI
10.1126/science.1091422