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- Title
Postnatal neurodevelopmental disorders: meeting at the synapse?
- Authors
Zoghbi, Huda Y
- Abstract
We often think of neurodevelopmental disorders as beginning before birth, and many certainly do. A handful, however, strike many months after birth, following a period of apparently normal growth and development. Autism and Rett syndrome are two such disorders, and here I consider some of their similarities at the phenotypic and pathogenic levels. I propose that both disorders result from disruption of postnatal or experience-dependent synaptic plasticity.
- Publication
Science (New York, N.Y.), 2003, Vol 302, Issue 5646, p826
- ISSN
1095-9203
- Publication type
Journal Article
- DOI
10.1126/science.1089071