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Title
Evolution of the protein repertoire.
Authors
Chothia, Cyrus; Gough, Julian; Vogel, Christine; Teichmann, Sarah A
Abstract
Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.
Publication
Science (New York, N.Y.), 2003, Vol 300, Issue 5626, p1701