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- Title
Traces of human migrations in Helicobacter pylori populations.
- Authors
Falush, Daniel; Wirth, Thierry; Linz, Bodo; Pritchard, Jonathan K; Stephens, Matthew; Kidd, Mark; Blaser, Martin J; Graham, David Y; Vacher, Sylvie; Perez-Perez, Guillermo I; Yamaoka, Yoshio; Mégraud, Francis; Otto, Kristina; Reichard, Ulrike; Katzowitsch, Elena; Wang, Xiaoyan; Achtman, Mark; Suerbaum, Sebastian
- Abstract
Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven populations and subpopulations with distinct geographical distributions. These modern populations derive their gene pools from ancestral populations that arose in Africa, Central Asia, and East Asia. Subsequent spread can be attributed to human migratory fluxes such as the prehistoric colonization of Polynesia and the Americas, the neolithic introduction of farming to Europe, the Bantu expansion within Africa, and the slave trade.
- Publication
Science (New York, N.Y.), 2003, Vol 299, Issue 5612, p1582
- ISSN
1095-9203
- Publication type
Journal Article
- DOI
10.1126/science.1080857