We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Postsynaptic signaling and plasticity mechanisms.
- Authors
Sheng, Morgan; Kim, Myung Jong
- Abstract
In excitatory synapses of the brain, specific receptors in the postsynaptic membrane lie ready to respond to the release of the neurotransmitter glutamate from the presynaptic terminal. Upon stimulation, these glutamate receptors activate multiple biochemical pathways that transduce signals into the postsynaptic neuron. Different kinds of synaptic activity elicit different patterns of postsynaptic signals that lead to short- or long-lasting strengthening or weakening of synaptic transmission. The complex molecular mechanisms that underlie postsynaptic signaling and plasticity are beginning to emerge.
- Publication
Science (New York, N.Y.), 2002, Vol 298, Issue 5594, p776
- ISSN
1095-9203
- Publication type
Journal Article
- DOI
10.1126/science.1075333