We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The danger model: a renewed sense of self.
- Authors
Matzinger, Polly
- Abstract
For over 50 years immunologists have based their thoughts, experiments, and clinical treatments on the idea that the immune system functions by making a distinction between self and nonself. Although this paradigm has often served us well, years of detailed examination have revealed a number of inherent problems. This Viewpoint outlines a model of immunity based on the idea that the immune system is more concerned with entities that do damage than with those that are foreign.
- Publication
Science (New York, N.Y.), 2002, Vol 296, Issue 5566, p301
- ISSN
1095-9203
- Publication type
Journal Article
- DOI
10.1126/science.1071059