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- Title
Unique chromatin remodeling and transcriptional regulation in spermatogenesis.
- Authors
Sassone-Corsi, Paolo
- Abstract
Most of our knowledge of transcriptional regulation comes from studies in somatic cells. However, increasing evidence reveals that gene regulation mechanisms are different in haploid germ cells. A number of highly specialized strategies operate during spermatogenesis. These include a unique chromatin reorganization program and the use of distinct promoter elements and specific transcription factors. Deciphering the rules governing transcriptional control during spermatogenesis will provide valuable insights of biomedical importance.
- Publication
Science (New York, N.Y.), 2002, Vol 296, Issue 5576, p2176
- ISSN
1095-9203
- Publication type
Journal Article
- DOI
10.1126/science.1070963