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- Title
Modeling lung deformation: a combined deformable image registration method with spatially varying Young's modulus estimates.
- Authors
Li, Min; Castillo, Edward; Zheng, Xiao-Lin; Luo, Hong-Yan; Castillo, Richard; Wu, Yi; Guerrero, Thomas
- Abstract
Respiratory motion introduces uncertainties in tumor location and lung deformation, which often results in difficulties calculating dose distributions in thoracic radiation therapy. Deformable image registration (DIR) has ability to describe respiratory-induced lung deformation, with which the radiotherapy techniques can deliver high dose to tumors while reducing radiation in surrounding normal tissue. The authors' goal is to propose a DIR method to overcome two main challenges of the previous biomechanical model for lung deformation, i.e., the requirement of precise boundary conditions and the lack of elasticity distribution.
- Publication
Medical physics, 2013, Vol 40, Issue 8, p081902
- ISSN
2473-4209
- Publication type
Journal Article
- DOI
10.1118/1.4812419