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- Title
Noise spatial nonuniformity and the impact of statistical image reconstruction in CT myocardial perfusion imaging.
- Authors
Lauzier, Pascal Theriault; Tang, Jie; Speidel, Michael A; Chen, Guang-Hong
- Abstract
To achieve high temporal resolution in CT myocardial perfusion imaging (MPI), images are often reconstructed using filtered backprojection (FBP) algorithms from data acquired within a short-scan angular range. However, the variation in the central angle from one time frame to the next in gated short scans has been shown to create detrimental partial scan artifacts when performing quantitative MPI measurements. This study has two main purposes. (1) To demonstrate the existence of a distinct detrimental effect in short-scan FBP, i.e., the introduction of a nonuniform spatial image noise distribution; this nonuniformity can lead to unexpectedly high image noise and streaking artifacts, which may affect CT MPI quantification. (2) To demonstrate that statistical image reconstruction (SIR) algorithms can be a potential solution to address the nonuniform spatial noise distribution problem and can also lead to radiation dose reduction in the context of CT MPI.
- Publication
Medical physics, 2012, Vol 39, Issue 7, p4079
- ISSN
0094-2405
- Publication type
Journal Article
- DOI
10.1118/1.4722983