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- Title
Toward automatic regional analysis of pulmonary function using inspiration and expiration thoracic CT.
- Authors
Murphy, Keelin; Pluim, Josien P W; van Rikxoort, Eva M; de Jong, Pim A; de Hoop, Bartjan; Gietema, Hester A; Mets, Onno; de Bruijne, Marleen; Lo, Pechin; Prokop, Mathias; van Ginneken, Bram
- Abstract
To analyze pulmonary function using a fully automatic technique which processes pairs of thoracic CT scans acquired at breath-hold inspiration and expiration, respectively. The following research objectives are identified to: (a) describe and systematically analyze the processing pipeline and its results; (b) verify that the quantitative, regional ventilation measurements acquired through CT are meaningful for pulmonary function analysis; (c) identify the most effective of the calculated measurements in predicting pulmonary function; and (d) demonstrate the potential of the system to deliver clinically important information not available through conventional spirometry.
- Publication
Medical physics, 2012, Vol 39, Issue 3, p1650
- ISSN
0094-2405
- Publication type
Journal Article
- DOI
10.1118/1.3687891